Medication that inhibit CYP2D6 exercise, like paroxetine and quinidine, may well trigger lowered clearance of oxycodone which could lead to a rise in oxycodone plasma concentrations. Concurrent administration of quinidine resulted in a rise in oxycodone Cmax by 11%, AUC by 13%, and t½ elim.Ritonavir or lopinavir/ritonavir greatly raise plasma conc
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